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9 met the criteria. These studies revealed that cocoon silk derivatives exhibit a wide range of tensile strength (1)
a material with promising applications in biomaterials and tissue engineering. Methods: We conducted a comprehensive systematic review adhering to PRISMA guidelines. Our focus was on the primary outcomes of tensile strength and elongation at break (1)
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and complications. Results: Out of the 192 silk-related studies (1)
and elongation at break (1)
and hypoallergenic properties (1)
and the secondary outcomes included other mechanical properties (1)
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Background: Despite cocoon silk’s well-known strength (1)
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from 0.464 to 483.9 MPa (with a median of 4.27 MPa) (1)
from 2.56% to 946.5% (with a median of 60.0%). Biomedical applications of cocoon silk derivatives span from tissue regeneration (n = 6) to energy harvesting (n = 4). Complications often arose from material fragility in non-optimized derivative components. Conclusions: While cocoon silk shows expansive promise due to its suitable mechanical properties and low complication risk (1)
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is of significance as it evaluates the mechanical properties and clinical potential of cocoon silk (1)
its potential medical applications remain largely unexplored. This review (1)
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plenty remains to be discovered. Future research is crucial to fully realizing its vast surgical and biomedical potential. (1)
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systematic review; silk; cocoon silk; mechanical properties; biomedicine (1)
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